An Unbiased View of phosphate buffer composition
This is often correct for hydrogen ions and bicarbonate. If bicarbonate is reabsorbed and/or acid is secreted into the urine, the pH becomes more alkaline (will increase). When bicarbonate just isn't reabsorbed or acid will not be excreted in the urine, pH gets to be more acidic (decreases). The metabolic payment through the renal system takes ext